Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15-34 years old).
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Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15-34 years old).
An association of Chlamydia pneumoniae with atherosclerosis of coronary and carotid arteries and aorta has been found by seroepidemiology and by demonstration of the organism in atheromata. Age-matched control tissue from persons without atherosclerosis was usually not available. We studied autopsy tissue from young persons, many with no atherosclerosis, to determine whether C. pneumoniae is pr...
متن کاملChlamydia pneumoniae, strain TWAR.
A new third species of Chiamydia, called C pneumoniae, has been established for the TWAR organism. We first thought that the new organism belonged to the C psittaci species because it was clearly not a C trachomatis.2’8 Subsequent studies showed that the organism was unique from both currently recognized species.8”#{176}”7”9 Justification for establishing a new species rests primarily on studie...
متن کاملIn vitro susceptibilities of Chlamydia pneumoniae (Chlamydia sp. strain TWAR).
The in vitro susceptibilities of two clinical isolates of Chlamydia pneumoniae from Brooklyn, N.Y., were determined for tetracycline, erythromycin, sulfamethoxazole, ciprofloxacin, and three new macrolides--azithromycin, clarithromycin, and roxithromycin. Clarithromycin was the most active drug tested, followed by the other macrolides, tetracycline, and ciprofloxacin.
متن کاملPrevalence of antibody to Chlamydia pneumoniae TWAR in japan.
Chlamydia pneumoniae TWAR is a newly recognized Chlamydia species that is a pathogen of respiratory tract infection. To clarify the endemic status of C. pneumoniae in Japan, we evaluated the incidence of C. pneumoniae antibody in 1,330 serum samples (660 from outpatients, 600 from normal individuals, and 70 from cord blood). The antibody titer was determined by a microimmunofluorescence test by...
متن کاملA mouse model of Chlamydia pneumoniae strain TWAR pneumonitis.
Chlamydia pneumoniae is a common cause of acute respiratory infections in humans. We evaluated mice as experimental animals for C. pneumoniae. Intranasal inoculation of Swiss Webster mice with C. pneumoniae induced a prolonged course of lung infection, as demonstrated by reisolation of organisms from lungs (at 42 days) and persistence of lung pathology (> 60 days). The lung pathology was charac...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1995
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.92.15.6911